Computational Scientist – Image Lab

The Intravital Microscopy and Gene Expression (IMAGE) lab focuses on visualisiing and decoding cell fate decisions in vivo using high fidelity mouse models of disease, intravital microscopy and single cell genomics. The lab applies and develops computational methods to better understand human disease. We take a collaborative approach, working closely with bioinformaticians, mathematicians and computer scientitsts to tackle problems that address critical unmet medical needs.

THE OPPORTUNITY

We are looking for a Computational Scientist with experience in analysing single cell data. Successful candidates will work on genomics studies with experimental and clinical researchers across Strategic Programs at Garvan. Projects include single cell and spatial transcriptomic studies of cancer and genetic diseases, using clinical samples or animal models. Successful candidates will contribute to all study stages, including design and planning, data analysis, interpretation and manuscript writing.

Salary: Up to $150k + 10.5% + salary packaging (depending on experience)

Employment Type: 1 year term contract

SNAPSHOT OF BENEFITS

• Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay (max. $15,900 general expenses + $2,650 meals/accom)

• Ample opportunities for on-going training and development

• Stimulating, diverse and highly international research environment

• Flexible work arrangements e.g. location, start / finish times etc

• 18 weeks paid parental leave for both parents including paid superannuation

• A range of additional leave types to meet your personal needs including cultural leave, conference leave, community service and study leave

• Discounted Health Insurance

• Lifestyle discounts with our community partners

WHAT YOU WILL DO

• Analysis of high-throughput datasets, including quality control, unsupervised and supervised analyses, with emphasis on biological interpretation

• Preparing figures for publication, contributing to manuscript writing

• Experimental design and planning

• Creating and maintaining modular and reusable workflows through use of container and workflow management technologies

• Developing best practices for computational workflows through evaluation/benchmarking of existing methods and/or original method development

• Staying informed on advances in computational methods, genomics, as well as building and maintaining biological domain expertise

• Contribute to internal education programs through designing and running workshops, mentoring, technical supervision, code reviews

ABOUT YOU

The key skills and experience include:

• PhD degree in a related area of science or engineering or equivalent experience

• Good statistical knowledge and programming skills

• Good knowledge of biology

• Previous experience working with next-generation sequencing data, such as single-cell sequencing, spatial transcriptomics, RNA-seq, targeted or whole-genome sequencing, ChIP-seq, ATAC-seq

• Publications commensurate with experience

• Comfortable working with Unix and in an HPC environment

• Proficient in at least one scripting language (R, Python)

• Familiar with version control systems

• Experience with software containers, workflow management systems, databases, cloud computing

• Highly developed written and verbal communications skills

ABOUT GARVAN

The Garvan Institute of Medical Research is an independent Medical Research Institute (MRI) in Sydney, delivering scientific and clinical impact on a global basis and in partnership with organisations that share our vision. We are proud to be one of Australia’s largest and most highly regarded MRI’s.

Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome.

We seek to see our world-class discovery research achieve life-changing impacts, not only for individual patients with rare diseases, but for the many thousands affected by complex, common disease.

Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging. We are always looking for culture ‘add’, not culture ‘fit’ and are building diverse teams with great sets of complementary styles and skills to help deliver our important work effectively.

HOW TO APPLY

To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. We are reviewing applications as they are received. If you think you’re the right person for this role, we’d love to hear how your capabilities, achievements and experience set you apart.