Postdoctoral Fellow/research Fellow

Classification: Academic Level A/B
Salary package: $78,940 – $121,857 per annum, plus 17% superannuation
Terms: Full Time, Fixed Term (up to 3 years)

• The project will be undertaken in an internationally recognised chromatin laboratory, which has established many new and complex techniques to study the link between chromatin structure and function.
• The project is an international collaboration with a world-renowned structural biologist that has expertise in the structure determination of nucleosomes in complex with nuclear factors using x-ray crystallography and cryoEM.  
• The project will be undertaken in a high-quality and collegial research environment that affords access to an impressive array of additional expertise, resources, and equipment.

Position overview

ANU has an international reputation for research and education relevant to the health and well-being of the population of Australia, as well as that of the developing world. This is achieved through discovery research, applied research in health service settings, research-led teaching in health and medical sciences, and the translation of research findings into practice and policy. The ANU College of Health and Medicine comprises the School of Medicine and Psychology, the John Curtin School of Medical Research and the National Centre for Epidemiology and Population Health. These schools work together to deliver world-class research and education across the spectrum of medicine and health-related fields, working in partnership with the health sector at local, national and international levels.  

While it is known that epigenetic modifications play a crucial role in regulating all aspects of genome function, a major gap in knowledge is how this second dimension of genomic information is functionally translated or interpreted to regulate specific patterns of gene expression. This project will reveal new fundamental principles of gene activation that include the identification of a new mechanism that relies on the interplay between chromatin-remodelling enzymes, histone posttranslational modifications and histone variants by using the latest approaches in protein purification, structural biology, and genome biology. Applicants will require strong skills in biochemical and/or structural techniques needed to study protein-protein or protein-DNA interactions, and be able to express and purify recombinant proteins. Experience in purifying proteins from living cells is desirable and having knowledge of the chromatin field would be advantageous

The John Curtin School of Medical Research constitutes a highly interactive and intellectually stimulating research environment within its three research divisions (Immunology, Neuroscience, and Genome and Cancer). It has a strong mentoring culture, giving junior scientists easy access to advice from more experienced colleagues. Links among researchers in the ANU College of Health and Medicine, and the College of Science and Environment gives access to a broader life science research context at the University. 

For further information about this position please contact Professor David Tremethick at [email protected] 

The University actively encourages applications from Aboriginal and Torres Strait Islander people. For more information on employment opportunities, contact our Indigenous Employment Consultant via: [email protected]  

ANU values diversity and inclusion and is committed to providing equal employment opportunities to those of all backgrounds and identities. For more information about staff equity at ANU, visit https://services.anu.edu.au/human-resources/respect-inclusion

Application information

In order to apply for this role please make sure that you upload the following documents:

• A statement addressing the selection criteria.
• A current curriculum vitae (CV) which includes the names and contact details of at least three referees (preferably including a current or previous supervisor). If your CV does not include referees, you can complete these online when prompted in the application form.
• Other documents, if required.

Applications which do not address the selection criteria may not be considered for the position.

Please note: The successful candidate will be required to undergo a background check during the recruitment process.  An offer of employment is conditional on satisfactory results.